|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:activatedBy
|
gptkb:AMP
gptkb:ADP
|
|
gptkbp:alias
|
gptkb:AMPKα1
gptkb:AMPK_alpha-1
gptkb:AMPK_catalytic_subunit_alpha-1
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:type_2_diabetes
gptkb:metabolic_syndrome
obesity
|
|
gptkbp:component
|
gptkb:AMP-activated_protein_kinase_(AMPK)_complex
|
|
gptkbp:encodes
|
gptkb:AMP-activated_protein_kinase_catalytic_subunit_alpha-1
|
|
gptkbp:Entrez_Gene_ID
|
5562
|
|
gptkbp:enzymeCommissionNumber
|
2.7.11.31
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
brain
heart
liver
adipose tissue
|
|
gptkbp:function
|
regulation of cellular energy homeostasis
|
|
gptkbp:gene
|
gptkb:PRKAA1
|
|
gptkbp:HGNC_ID
|
9381
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
AMPK1A
|
|
gptkbp:inhibitedBy
|
gptkb:ATP
|
|
gptkbp:involves
|
glucose uptake
cell growth regulation
autophagy
fatty acid oxidation
metabolic stress response
|
|
gptkbp:locatedOnChromosome
|
5p13.1
|
|
gptkbp:molecularWeight
|
63 kDa
|
|
gptkbp:OMIM
|
602739
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Prkaa1
|
|
gptkbp:PDB
|
gptkb:4CFE
4CFF
|
|
gptkbp:phosphorylates
|
gptkb:CAMKK2
gptkb:LKB1
|
|
gptkbp:regulates
|
gptkb:mTOR_pathway
lipid metabolism
protein synthesis
glycogen synthesis
cellular ATP levels
|
|
gptkbp:subunit
|
AMPK heterotrimeric complex
|
|
gptkbp:UniProtID
|
gptkb:Q13131
|
|
gptkbp:bfsParent
|
gptkb:PRKAA1_gene
|
|
gptkbp:bfsLayer
|
8
|