|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:AMPK_alpha-1
gptkb:protein_kinase,_AMP-activated,_alpha_1_catalytic_subunit
|
|
gptkbp:amendedBy
|
phosphorylation
|
|
gptkbp:biologicalProcess
|
protein serine/threonine kinase activity
metabolic process
response to cellular stress
|
|
gptkbp:encodes
|
gptkb:AMP-activated_protein_kinase_catalytic_subunit_alpha-1
|
|
gptkbp:Entrez_Gene_ID
|
50794
ENSMUSG00000027945
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
brain
liver
adipose tissue
|
|
gptkbp:function
|
regulation of cellular energy homeostasis
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Prkaa1
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_15_(mouse)
|
|
gptkbp:location
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:mutationAssociatedWith
|
altered energy metabolism
impaired glucose homeostasis
|
|
gptkbp:organism
|
gptkb:Mus_musculus
|
|
gptkbp:orthologIn
|
gptkb:PRKAA1_(human)
|
|
gptkbp:pathway
|
AMPK signaling pathway
|
|
gptkbp:proteinFamily
|
gptkb:AMP-activated_protein_kinase_family
|
|
gptkbp:regulates
|
lipid metabolism
cell growth
glucose uptake
autophagy
fatty acid oxidation
|
|
gptkbp:UniProtID
|
Q9Z2K1
|
|
gptkbp:bfsParent
|
gptkb:PRKAA1
gptkb:Protein_kinase,_AMP-activated,_alpha_1_catalytic_subunit
|
|
gptkbp:bfsLayer
|
7
|