AMP-activated protein kinase (AMPK) complex

URI: https://gptkb.org/entity/AMP-activated_protein_kinase_(AMPK)_complex
GPTKB entity
Statements (45)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:activatedBy gptkb:AICAR
gptkb:metformin
gptkb:AMP
gptkb:ADP
exercise
gptkbp:composedOf AMPK beta subunit
AMPK gamma subunit
AMPK alpha subunit
gptkbp:discoveredBy gptkb:D._Grahame_Hardie
gptkbp:EC_number 2.7.11.31
gptkbp:foundIn eukaryotic cells
gptkbp:function cellular energy sensor
regulation of metabolism
gptkbp:gene gptkb:PRKAA1
gptkb:PRKAA2
gptkb:PRKAB1
gptkb:PRKAB2
gptkb:PRKAG1
gptkb:PRKAG2
gptkb:PRKAG3
gptkbp:GO_term gptkb:GO:0004674
https://www.w3.org/2000/01/rdf-schema#label AMP-activated protein kinase (AMPK) complex
gptkbp:inhibitedBy gptkb:ATP
gptkb:compound_C
gptkbp:involvedIn gptkb:type_2_diabetes
obesity
cancer metabolism
response to metabolic stress
exercise adaptation
gptkbp:locale gptkb:nucleus
gptkb:cytoplasm
gptkbp:otherName gptkb:AMPK
5'-AMP-activated protein kinase
gptkbp:phosphorylates gptkb:HMG-CoA_reductase
gptkb:acetyl-CoA_carboxylase
gptkbp:regulates gptkb:mTOR_pathway
glucose uptake
protein synthesis
autophagy
fatty acid oxidation
gptkbp:UniProtID gptkb:Q13131
gptkbp:bfsParent gptkb:PRKAA2
gptkb:PRKAG2
gptkbp:bfsLayer 7