Statements (66)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:associated_with |
gptkb:Peutz-Jeghers_syndrome
cancer predisposition |
| gptkbp:author |
G. J. A. van der Velden
|
| gptkbp:discovered_by |
gptkb:1997
|
| gptkbp:function |
tumor suppressor
|
| gptkbp:genetic_studies |
causes cancer
|
| gptkbp:has_role |
energy homeostasis
|
| https://www.w3.org/2000/01/rdf-schema#label |
LKB1
|
| gptkbp:initiated_by |
gptkb:AMP-activated_protein_kinase
lipogenesis m TOR pathway |
| gptkbp:interacts_with |
gptkb:AMPK
gptkb:Raptor gptkb:p53 TSC2 Rictor |
| gptkbp:involved_in |
gptkb:diabetes
apoptosis cell cycle regulation cellular homeostasis cellular metabolism cellular stress response cellular transport immune response mitochondrial function inflammation metabolic syndrome obesity cardiovascular diseases cellular proliferation cellular senescence tumor microenvironment cell metabolism cellular differentiation differentiation cellular signaling pathways insulin signaling neurodegeneration cellular adhesion autophagy cellular communication stem cell maintenance cellular signaling cellular organization tissue homeostasis vascular biology neoplasia cellular repair mechanisms cellular adaptation cellular apoptosis cellular integrity cellular migration cell polarity cellular autophagy cellular necrosis |
| gptkbp:is_expressed_in |
lung tissue
pancreatic tissue intestinal tissue |
| gptkbp:is_located_in |
chromosome 19
|
| gptkbp:located_in |
gptkb:Atom
|
| gptkbp:promoter |
STK11
|
| gptkbp:regulates |
cell growth
glucose metabolism |
| gptkbp:bfsParent |
gptkb:AMP-activated_protein_kinase
|
| gptkbp:bfsLayer |
8
|