Statements (55)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:Genetics
|
| gptkbp:associated_with |
gptkb:early_onset_Alzheimer's_disease
congenital heart defects hypotonia increased risk of leukemia |
| gptkbp:caused_by |
gptkb:trisomy_21
|
| gptkbp:characterized_by |
intellectual disability
distinctive facial features |
| gptkbp:diagnosis |
chromosomal analysis
|
| gptkbp:first_described_by |
gptkb:John_Langdon_Down
|
| https://www.w3.org/2000/01/rdf-schema#label |
Down syndrome
|
| gptkbp:is_involved_in |
gptkb:Global_Down_Syndrome_Foundation
gptkb:Down_Syndrome_International gptkb:National_Down_Syndrome_Society |
| gptkbp:lifespan |
around 60 years
|
| gptkbp:prevalence |
1 in 700 births
|
| gptkbp:symptoms |
gptkb:depression
gptkb:attention_deficit_hyperactivity_disorder_(ADHD) anxiety schizophrenia seizures social challenges vision problems bipolar disorder repetitive behaviors sensory processing issues skin conditions behavioral issues sleep apnea heart defects emotional challenges short stature autism spectrum disorder learning difficulties communication difficulties gastrointestinal issues dental issues hearing problems short neck thyroid problems small hands and feet obsessive-compulsive disorder (OCD) delayed development excessive flexibility poor muscle tone protruding tongue self-care challenges single transverse palmar crease slanted eyes |
| gptkbp:treatment |
physical therapy
occupational therapy speech therapy early intervention programs |
| gptkbp:bfsParent |
gptkb:Oncology
|
| gptkbp:bfsLayer |
4
|