Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeSplicing |
gptkb:TP53_gene
|
| gptkbp:domain |
DNA-binding domain
oligomerization domain transactivation domain |
| gptkbp:encodedBy |
gptkb:TP53_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
tumor suppressor
transcription factor |
| gptkbp:hasIsoform |
gptkb:p53
|
| https://www.w3.org/2000/01/rdf-schema#label |
p53α
|
| gptkbp:interactsWith |
gptkb:BAX
gptkb:p21 gptkb:MDM2 gptkb:CHK2 ATM |
| gptkbp:locale |
gptkb:nucleus
|
| gptkbp:molecularWeight |
~53 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:cancer
|
| gptkbp:postTranslationalModification |
phosphorylation
ubiquitination acetylation |
| gptkbp:regulates |
apoptosis
DNA repair senescence cell cycle arrest |
| gptkbp:bfsParent |
gptkb:P53_HUMAN
|
| gptkbp:bfsLayer |
7
|