|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:TrkA
gptkb:NTRK1
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:congenital_insensitivity_to_pain_with_anhidrosis
|
|
gptkbp:binds
|
gptkb:nerve_growth_factor
|
|
gptkbp:domain
|
immunoglobulin-like domain
tyrosine kinase domain
|
|
gptkbp:encodedBy
|
gptkb:NTRK1_gene
|
|
gptkbp:Entrez_Gene_ID
|
4914
|
|
gptkbp:expressedIn
|
gptkb:nervous_system
sympathetic neurons
|
|
gptkbp:formsComplexWith
|
gptkb:NGF
gptkb:p75NTR
|
|
gptkbp:function
|
gptkb:receptor_tyrosine_kinase
neurotrophin receptor
|
|
gptkbp:GOID
|
gptkb:GO:0005006
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
p140-TrkA
|
|
gptkbp:involvedIn
|
signal transduction
neuronal differentiation
neuronal survival
|
|
gptkbp:locatedOnChromosome
|
1q23.1
|
|
gptkbp:location
|
gptkb:plasma_membrane
|
|
gptkbp:molecularWeight
|
140 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:PDB
|
gptkb:1WWW
|
|
gptkbp:phosphorylates
|
tyrosine residues
|
|
gptkbp:reactomeID
|
R-HSA-166520
|
|
gptkbp:UniProtID
|
gptkb:P04629
|
|
gptkbp:bfsParent
|
gptkb:NTRK1
gptkb:NTRK1_gene
gptkb:HGNC:8007
|
|
gptkbp:bfsLayer
|
7
|