octamer-binding transcription factor 4

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein transcription factor
gptkbp:alias	gptkb:OCT3 gptkb:POU5F1
gptkbp:associatedWith	cellular reprogramming
gptkbp:biologicalProcess	DNA-binding transcription activator activity
gptkbp:Entrez_Gene_ID	gptkb:ENSG00000204531 5460
gptkbp:expressedIn	embryonic stem cells
gptkbp:function	maintenance of stem cell self-renewal regulation of pluripotency
gptkbp:gene	gptkb:OCT4 gptkb:POU5F1
gptkbp:HGNC_ID	9221
https://www.w3.org/2000/01/rdf-schema#label	octamer-binding transcription factor 4
gptkbp:involves	early embryonic development
gptkbp:locatedIn	gptkb:nucleus
gptkbp:locatedOnChromosome	6p21.33
gptkbp:OMIM	164177
gptkbp:orthologInMouse	Pou5f1
gptkbp:proteinFamily	POU domain transcription factors
gptkbp:regulates	gptkb:NANOG gptkb:KLF4 gptkb:CDH1 gptkb:ESRRB gptkb:DUSP6 gptkb:SOX2 gptkb:MYC gptkb:TCL1A gptkb:TERT gptkb:ID2 gptkb:ID3 gptkb:ID4 gptkb:FGF4 gene expression ID1 LEFTY1 SALL4 UTF1 PRDM14 ZIC3 DPPA2 DPPA3 DPPA4 DPPA5 GDF3 LEFTY2 LIN28A LIN28B REX1 TDGF1 ZFP42
gptkbp:structure	contains homeobox domain contains POU-specific domain
gptkbp:UniProtID	gptkb:Q01860
gptkbp:used_as_marker_for	pluripotency
gptkbp:bfsParent	gptkb:POU5F1
gptkbp:bfsLayer	7