|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:alternativeName
|
gptkb:MAO-A
gptkb:amine_oxidase_(flavin-containing)_A
gptkb:monoamine_oxidase_type_A
|
|
gptkbp:associatedWith
|
gptkb:depression
gptkb:autism_spectrum_disorder
gptkb:panic_disorder
gptkb:Brunner_syndrome
aggressive behavior
antisocial behavior
|
|
gptkbp:catalyzes
|
oxidative deamination of monoamines
|
|
gptkbp:cofactor
|
gptkb:FAD
|
|
gptkbp:EC_number
|
1.4.3.4
|
|
gptkbp:encodedBy
|
gptkb:MAOA_gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:MAOA
|
|
gptkbp:expressedIn
|
gptkb:placenta
gptkb:small_intestine
brain
liver
|
|
gptkbp:foundIn
|
humans
other mammals
|
|
gptkbp:function
|
degrades neurotransmitters
|
|
gptkbp:gene
|
gptkb:MAOA
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
6833
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
monoamine oxidase A
|
|
gptkbp:inhibitedBy
|
gptkb:phenelzine
gptkb:clorgyline
gptkb:moclobemide
|
|
gptkbp:locatedIn
|
mitochondrial outer membrane
|
|
gptkbp:locatedOnChromosome
|
Xp11.3
|
|
gptkbp:molecularWeight
|
59 kDa
|
|
gptkbp:OMIM
|
309850
|
|
gptkbp:orthologInMouse
|
gptkb:Maoa
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:substrate
|
gptkb:tyramine
dopamine
norepinephrine
serotonin
|
|
gptkbp:UniProtID
|
gptkb:P21397
|
|
gptkbp:bfsParent
|
gptkb:monoamine_oxidase_inhibitors
|
|
gptkbp:bfsLayer
|
6
|