Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:abbreviation |
gptkb:MAO-A
|
| gptkbp:associatedWith |
gptkb:depression
anxiety mood regulation |
| gptkbp:biologicalProcess |
neurotransmitter catabolic process
amine oxidase activity |
| gptkbp:catalyzes |
oxidative deamination of monoamines
|
| gptkbp:cofactor |
gptkb:FAD
|
| gptkbp:discoveredBy |
gptkb:Mary_Bernheim
|
| gptkbp:discoveredIn |
1928
|
| gptkbp:drug_target_for |
antidepressants
anxiolytics |
| gptkbp:EC_number |
1.4.3.4
|
| gptkbp:foundIn |
gptkb:human
other mammals |
| gptkbp:gene |
gptkb:MAOA
|
| gptkbp:GO_term |
gptkb:GO:0008131
|
| https://www.w3.org/2000/01/rdf-schema#label |
monoamine oxidase type A
|
| gptkbp:inhibitedBy |
gptkb:phenelzine
gptkb:clorgyline gptkb:moclobemide |
| gptkbp:locatedOnChromosome |
Xp11.3
|
| gptkbp:location |
outer mitochondrial membrane
|
| gptkbp:relatedTo |
gptkb:monoamine_oxidase_type_B
|
| gptkbp:structure |
dimer
|
| gptkbp:substrate |
gptkb:tyramine
dopamine norepinephrine serotonin |
| gptkbp:UniProtID |
gptkb:P21397
|
| gptkbp:bfsParent |
gptkb:monoamine_oxidase_A
|
| gptkbp:bfsLayer |
7
|