|
gptkbp:instanceOf
|
gptkb:drug
antidepressant
monoamine oxidase inhibitor
|
|
gptkbp:approvedBy
|
1961
|
|
gptkbp:ATCCode
|
gptkb:N06AF03
|
|
gptkbp:brand
|
gptkb:Nardil
|
|
gptkbp:CASNumber
|
51-71-6
|
|
gptkbp:chemicalFormula
|
C8H12N2
|
|
gptkbp:color
|
white to off-white powder
|
|
gptkbp:contraindication
|
gptkb:liver_disease
gptkb:pheochromocytoma
congestive heart failure
cerebrovascular disease
|
|
gptkbp:discoveredBy
|
gptkb:Parke-Davis
|
|
gptkbp:drugInteraction
|
gptkb:SSRIs
gptkb:TCAs
gptkb:sympathomimetics
tyramine-containing foods
|
|
gptkbp:eliminationHalfLife
|
11.6 hours
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
phenelzine
|
|
gptkbp:IUPACName
|
gptkb:2-phenylethylhydrazine
|
|
gptkbp:KEGGID
|
D08367
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
irreversible inhibition of monoamine oxidase
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
136.19 g/mol
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL1082
7946
8241
|
|
gptkbp:riskFactor
|
gptkb:serotonin_syndrome
hypertensive crisis with tyramine
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
gptkb:orthostatic_hypotension
dizziness
weight gain
insomnia
dry mouth
sexual dysfunction
|
|
gptkbp:storage
|
room temperature
|
|
gptkbp:UNII
|
U4VZ2RTK5M
|
|
gptkbp:usedFor
|
gptkb:depression
gptkb:panic_disorder
anxiety disorders
|
|
gptkbp:bfsParent
|
gptkb:monoamine_oxidase_inhibitors
gptkb:MAO_inhibitors
|
|
gptkbp:bfsLayer
|
6
|