|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:depression
gptkb:MAOB_gene
gptkb:autism_spectrum_disorder
gptkb:panic_disorder
gptkb:Brunner_syndrome
ADHD
substance abuse
aggression
mood disorders
behavioral traits
antisocial behavior
|
|
gptkbp:clinicalTrialPhase
|
genetic testing for Brunner syndrome
|
|
gptkbp:discoveredBy
|
Mary-Louise Brunner
|
|
gptkbp:encodes
|
gptkb:monoamine_oxidase_A
|
|
gptkbp:Entrez_Gene_ID
|
4128
|
|
gptkbp:enzymeCommissionNumber
|
EC 1.4.3.4
|
|
gptkbp:expressedIn
|
gptkb:placenta
brain
liver
|
|
gptkbp:fullName
|
Monoamine oxidase A gene
|
|
gptkbp:function
|
catalyzes the oxidative deamination of amines
|
|
gptkbp:gene
|
gptkb:MAOA
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasPolymorphism
|
variable number tandem repeat (VNTR) in promoter
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
HGNC:6833
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MAOA gene
|
|
gptkbp:inhibitedBy
|
gptkb:phenelzine
gptkb:tranylcypromine
gptkb:clorgyline
gptkb:moclobemide
|
|
gptkbp:length
|
15 exons
|
|
gptkbp:locatedOnChromosome
|
gptkb:X_chromosome
Xp11.3
|
|
gptkbp:mutationAssociatedWith
|
intellectual disability
impulse control disorder
|
|
gptkbp:OMIM
|
309850
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Maoa
|
|
gptkbp:proteinFamily
|
flavin-containing amine oxidoreductase
|
|
gptkbp:referenceGenome
|
NM_000240
|
|
gptkbp:regulates
|
dopamine metabolism
norepinephrine metabolism
serotonin metabolism
|
|
gptkbp:UniProtID
|
gptkb:P21397
|
|
gptkbp:bfsParent
|
gptkb:monoamine_oxidase
gptkb:MAO-A
gptkb:monoamine_oxidase_A
|
|
gptkbp:bfsLayer
|
7
|