|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:MAO-A
gptkb:amine_oxidase_(flavin-containing)_A
|
|
gptkbp:associatedWith
|
neurotransmitter metabolism
dopamine metabolism
norepinephrine metabolism
serotonin metabolism
|
|
gptkbp:discoveredBy
|
gptkb:Mary_Bernheim
|
|
gptkbp:discoveredIn
|
1928
|
|
gptkbp:encodes
|
monoamine oxidase A enzyme
|
|
gptkbp:Entrez_Gene_ID
|
4128
|
|
gptkbp:enzymeCommissionNumber
|
1.4.3.4
|
|
gptkbp:expressedIn
|
gptkb:placenta
brain
liver
|
|
gptkbp:fullName
|
gptkb:monoamine_oxidase_A
|
|
gptkbp:function
|
catalyzes the oxidative deamination of monoamines
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GO_term
|
mitochondrion
oxidoreductase activity
amine oxidase activity
|
|
gptkbp:hasPolymorphism
|
R297R
T941G
uVNTR (upstream variable number tandem repeat)
|
|
gptkbp:HGNC_ID
|
6833
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MAOA
|
|
gptkbp:inhibitedBy
|
gptkb:phenelzine
gptkb:clorgyline
gptkb:moclobemide
|
|
gptkbp:length
|
527 amino acids
|
|
gptkbp:locatedOn
|
gptkb:X_chromosome
|
|
gptkbp:locatedOnChromosome
|
Xp11.3
|
|
gptkbp:mutationAssociatedWith
|
gptkb:Brunner_syndrome
aggression
antisocial behavior
|
|
gptkbp:OMIM
|
309850
|
|
gptkbp:orthologInMouse
|
gptkb:Maoa
|
|
gptkbp:proteinFamily
|
flavin-containing amine oxidase family
|
|
gptkbp:regulates
|
promoter VNTR polymorphism
|
|
gptkbp:relatedTo
|
gptkb:MAOB
|
|
gptkbp:significance
|
gptkb:depression
gptkb:autism_spectrum_disorder
ADHD
anxiety
substance abuse
mood disorders
psychiatric disorders
|
|
gptkbp:UniProtID
|
gptkb:P21397
|
|
gptkbp:bfsParent
|
gptkb:MAO-A
gptkb:monoamine_oxidase_A
|
|
gptkbp:bfsLayer
|
7
|