|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:actsOn
|
gptkb:tyramine
dopamine
norepinephrine
serotonin
epinephrine
|
|
gptkbp:catalyzes
|
oxidative deamination of monoamines
|
|
gptkbp:cofactor
|
gptkb:FAD_(flavin_adenine_dinucleotide)
|
|
gptkbp:discoveredBy
|
gptkb:Mary_Bernheim
|
|
gptkbp:discoveredIn
|
1928
|
|
gptkbp:EC_number
|
1.4.3.4
|
|
gptkbp:encodedBy
|
gptkb:MAOA_gene
gptkb:MAOB_gene
|
|
gptkbp:foundIn
|
gptkb:nervous_system
gastrointestinal tract
liver
mitochondria
|
|
gptkbp:hasIsoform
|
gptkb:MAO-A
gptkb:MAO-B
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
monoamine oxidase
|
|
gptkbp:inhibitedBy
|
gptkb:monoamine_oxidase_inhibitors
|
|
gptkbp:involves
|
neurotransmitter metabolism
|
|
gptkbp:presentIn
|
all mammals
many non-mammalian species
|
|
gptkbp:relatedTo
|
gptkb:Alzheimer's_disease
gptkb:Parkinson's_disease
gptkb:depression
schizophrenia
anxiety disorders
|
|
gptkbp:structure
|
dimeric protein
|
|
gptkbp:systematicName
|
amine:oxygen oxidoreductase (deaminating)
|
|
gptkbp:target
|
antidepressant drugs
antiparkinsonian drugs
|
|
gptkbp:bfsParent
|
gptkb:Dopamine
gptkb:Adrenaline
gptkb:Serotonin
gptkb:Norepinephrine
|
|
gptkbp:bfsLayer
|
6
|