|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:activity
|
oxidoreductase
|
|
gptkbp:alternativeName
|
gptkb:amine_oxidase_(flavin-containing)_B
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:Parkinson's_disease
|
|
gptkbp:cofactor
|
gptkb:FAD_(flavin_adenine_dinucleotide)
|
|
gptkbp:discoveredBy
|
gptkb:Mary_Bernheim
|
|
gptkbp:discoveredIn
|
1928
|
|
gptkbp:EC_number
|
1.4.3.4
|
|
gptkbp:encodedBy
|
gptkb:MAOB_gene
|
|
gptkbp:expressedIn
|
brain
liver
platelets
|
|
gptkbp:fullName
|
gptkb:Monoamine_oxidase_B
|
|
gptkbp:function
|
catalyzes oxidative deamination of monoamines
|
|
gptkbp:gene
|
gptkb:MAOB
|
|
gptkbp:GO_term
|
gptkb:GO:0008131
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MAO-B
|
|
gptkbp:inhibitedBy
|
gptkb:rasagiline
gptkb:selegiline
gptkb:safinamide
|
|
gptkbp:locatedIn
|
outer mitochondrial membrane
|
|
gptkbp:locatedOnChromosome
|
Xp11.3
|
|
gptkbp:molecularWeight
|
58 kDa
|
|
gptkbp:PDB
|
gptkb:1GOS
|
|
gptkbp:relatedTo
|
gptkb:MAO-A
|
|
gptkbp:structure
|
dimer
|
|
gptkbp:substrate
|
gptkb:benzylamine
dopamine
phenylethylamine
|
|
gptkbp:targetOfDrug
|
antiparkinsonian drugs
|
|
gptkbp:UniProtID
|
gptkb:P27338
|
|
gptkbp:bfsParent
|
gptkb:MAO_inhibitors
|
|
gptkbp:bfsLayer
|
6
|