integrin alpha-M beta-2 complex
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:CR3
gptkb:Mac-1 gptkb:CD11b/CD18 |
| gptkbp:binds |
gptkb:ICAM-1
gptkb:iC3b |
| gptkbp:composedOf |
integrin alpha-M
integrin beta-2 |
| gptkbp:deficiencyCauses |
gptkb:leukocyte_adhesion_deficiency_type_1
|
| gptkbp:foundIn |
gptkb:leukocytes
|
| gptkbp:function |
immune response
phagocytosis cell adhesion |
| gptkbp:geneEncodingAlphaSubunit |
gptkb:ITGAM
|
| gptkbp:geneEncodingBetaSubunit |
gptkb:ITGB2
|
| https://www.w3.org/2000/01/rdf-schema#label |
integrin alpha-M beta-2 complex
|
| gptkbp:involvedIn |
inflammation
leukocyte migration |
| gptkbp:locatedOnChromosome |
16p11.2 (ITGAM)
21q22.3 (ITGB2) |
| gptkbp:structureType |
heterodimer
|
| gptkbp:bfsParent |
gptkb:integrin_alpha_M_(CD11b)
|
| gptkbp:bfsLayer |
7
|