|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
leukemia
infertility
|
|
gptkbp:discoveredBy
|
Gough et al.
|
|
gptkbp:discoveredIn
|
1987
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000128313
|
|
gptkbp:fullName
|
gptkb:Leukemia_Inhibitory_Factor
|
|
gptkbp:function
|
cytokine
regulates cell differentiation
induces hematopoietic cell differentiation
maintains pluripotency in embryonic stem cells
|
|
gptkbp:gene
|
gptkb:LIF_gene
gptkb:LIF
|
|
gptkbp:HGNC_ID
|
6596
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
human LIF
|
|
gptkbp:locatedOnChromosome
|
22q12.1
|
|
gptkbp:medicalUse
|
used in stem cell culture
|
|
gptkbp:molecularWeight
|
~20 kDa
|
|
gptkbp:OMIM
|
159540
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:pathway
|
gptkb:MAPK_pathway
gptkb:JAK/STAT_pathway
|
|
gptkbp:PDB
|
gptkb:1EMR
|
|
gptkbp:recipient
|
gptkb:gp130
gptkb:LIF_receptor_(LIFR)
|
|
gptkbp:RefSeq
|
NM_002309
|
|
gptkbp:secretes
|
yes
|
|
gptkbp:structure
|
gptkb:protein
|
|
gptkbp:UniProtID
|
gptkb:P15018
|
|
gptkbp:bfsParent
|
gptkb:bovine_LIF
gptkb:mouse_LIF
gptkb:rat_LIF
|
|
gptkbp:bfsLayer
|
8
|