Statements (44)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:G_protein-coupled_receptor |
| gptkbp:binds |
gptkb:histamine
|
| gptkbp:encodedBy |
gptkb:HRH1_gene
|
| gptkbp:enemyOf |
gptkb:olopatadine
gptkb:cetirizine gptkb:loratadine gptkb:promethazine gptkb:desloratadine gptkb:cyproheptadine gptkb:azelastine gptkb:levocetirizine gptkb:fexofenadine gptkb:bilastine diphenhydramine antihistamines chlorpheniramine brompheniramine 2-(3-trifluoromethylphenyl)histamine acrivastine clemastine dexchlorpheniramine doxylamine ebastine emastine hydroxyzine meclizine mizolastine rupatadine triprolidine |
| gptkbp:expressedIn |
brain
lungs endothelial cells smooth muscle |
| gptkbp:function |
increases vascular permeability
regulates smooth muscle contraction mediates allergic response |
| https://www.w3.org/2000/01/rdf-schema#label |
histamine receptor H1
|
| gptkbp:locatedIn |
gptkb:cell_membrane
|
| gptkbp:locatedOnChromosome |
3p25
|
| gptkbp:type |
Gq/11 protein pathway
|
| gptkbp:UniProtID |
gptkb:P35367
|
| gptkbp:bfsParent |
gptkb:H1
|
| gptkbp:bfsLayer |
6
|