|
gptkbp:instanceOf
|
gptkb:drug
antihistamine
|
|
gptkbp:approvedBy
|
2001
|
|
gptkbp:ATCCode
|
gptkb:R06AX27
|
|
gptkbp:availableOn
|
gptkb:tablet
oral solution
orodispersible tablet
|
|
gptkbp:brand
|
gptkb:Aerius
gptkb:Clarinex
|
|
gptkbp:CASNumber
|
100643-71-8
|
|
gptkbp:chemicalClass
|
tricyclic antihistamine
|
|
gptkbp:compatibleWith
|
significant drowsiness
|
|
gptkbp:contraindication
|
hypersensitivity to desloratadine
|
|
gptkbp:discoveredBy
|
gptkb:Schering-Plough
|
|
gptkbp:eliminationHalfLife
|
27 hours
|
|
gptkbp:excretion
|
urine
feces
|
|
gptkbp:hasMolecularFormula
|
C19H19ClN2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
desloratadine
|
|
gptkbp:interactsWith
|
gptkb:azithromycin
gptkb:erythromycin
gptkb:ketoconazole
gptkb:fluoxetine
cimetidine
|
|
gptkbp:isomerOf
|
gptkb:loratadine
|
|
gptkbp:IUPACName
|
gptkb:8-chloro-6,11-dihydro-11-(4-piperidylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
|
|
gptkbp:KEGGID
|
D07713
|
|
gptkbp:legalStatus
|
prescription only (in some countries)
over-the-counter (in some countries)
|
|
gptkbp:mechanismOfAction
|
selective H1 receptor antagonist
|
|
gptkbp:MedlinePlusID
|
a602002
|
|
gptkbp:metabolism
|
gptkb:loratadine
|
|
gptkbp:patentExpired
|
2012 (US)
|
|
gptkbp:pregnancyCategory
|
B1
Category C (US)
|
|
gptkbp:proteinBinding
|
83% to 87%
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL1201310
gptkb:DB00967
50995
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
fatigue
headache
dry mouth
|
|
gptkbp:synonym
|
gptkb:5H-benzo[5,6]cyclohepta[1,2-b]pyridine,_8-chloro-6,11-dihydro-11-(4-piperidylidene)-
|
|
gptkbp:UNII
|
OGG8L647I7
|
|
gptkbp:usedFor
|
gptkb:chronic_idiopathic_urticaria
allergic rhinitis
|
|
gptkbp:bfsParent
|
gptkb:Clarinex
|
|
gptkbp:bfsLayer
|
5
|