|
gptkbp:instanceOf
|
antihistamine
|
|
gptkbp:approvedBy
|
1993
|
|
gptkbp:ATCCode
|
gptkb:R06AX13
|
|
gptkbp:availableOn
|
gptkb:sugar
gptkb:tablet
disintegrating tablet
|
|
gptkbp:brand
|
gptkb:Claritin
gptkb:Alavert
|
|
gptkbp:CASNumber
|
79794-75-5
|
|
gptkbp:chemicalFormula
|
gptkb:C22H23ClN2O2
|
|
gptkbp:contraindication
|
severe liver impairment
|
|
gptkbp:cost
|
low
|
|
gptkbp:developedBy
|
gptkb:Schering-Plough
|
|
gptkbp:discoveredIn
|
1981
|
|
gptkbp:drugClass
|
second-generation antihistamine
|
|
gptkbp:eliminationHalfLife
|
8 hours
|
|
gptkbp:excretion
|
urine
feces
|
|
gptkbp:genericName
|
yes
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
loratadine
|
|
gptkbp:interactsWith
|
gptkb:erythromycin
gptkb:ketoconazole
cimetidine
|
|
gptkbp:KEGGID
|
gptkb:D08170
|
|
gptkbp:legalStatus
|
over-the-counter
|
|
gptkbp:mechanismOfAction
|
histamine H1 receptor antagonist
|
|
gptkbp:MedlinePlusID
|
a697038
|
|
gptkbp:MeSH_ID
|
gptkb:D017180
|
|
gptkbp:metabolism
|
gptkb:desloratadine
liver
|
|
gptkbp:molecularWeight
|
382.88 g/mol
|
|
gptkbp:notRecommendedFor
|
children under 2 years
|
|
gptkbp:pregnancyCategory
|
B (US)
|
|
gptkbp:prescriptionStatus
|
OTC in US
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL953
gptkb:DB00455
3957
|
|
gptkbp:riskOfDrowsiness
|
low
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
headache
drowsiness
dry mouth
|
|
gptkbp:soldIn
|
over 100 countries
|
|
gptkbp:solubility
|
practically insoluble in water
|
|
gptkbp:UNII
|
J60AR2IKIC
|
|
gptkbp:usedFor
|
allergic rhinitis
urticaria
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
yes
|
|
gptkbp:bfsParent
|
gptkb:Clarinex
|
|
gptkbp:bfsLayer
|
5
|