azelastine

GPTKB entity

Statements (37)
Predicate Object
gptkbp:instanceOf gptkb:chemical_compound
antihistamine
gptkbp:approvedBy 1990s
gptkbp:ATCCode R01AC03
gptkbp:brand Astelin
Astepro
Optivar
gptkbp:CASNumber 58581-89-8
gptkbp:discoveredBy Meda Pharma
gptkbp:eliminationHalfLife 22 hours
gptkbp:excretion urine
feces
gptkbp:hasMolecularFormula C22H24ClN3O
https://www.w3.org/2000/01/rdf-schema#label azelastine
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction histamine H1 receptor antagonist
gptkbp:meltingPoint 225-226°C
gptkbp:metabolism liver
gptkbp:pregnancyCategory C (US)
gptkbp:PubChem_CID 2267
2179
CHEMBL1201312
DB00972
gptkbp:routeOfAdministration nasal
ophthalmic
gptkbp:sideEffect headache
drowsiness
bitter taste
nasal irritation
gptkbp:synonym 4-[(4-chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1(2H)-phthalazinone
gptkbp:UNII L16O9V2TSM
gptkbp:usedFor allergic rhinitis
allergic conjunctivitis
vasomotor rhinitis
gptkbp:bfsParent gptkb:R06AE07
gptkb:antihistamine
gptkbp:bfsLayer 6