|
gptkbp:instanceOf
|
gptkb:drug
antihistamine
|
|
gptkbp:approvedBy
|
gptkb:European_Union
gptkb:United_States
2001
|
|
gptkbp:ATCCode
|
R06AE09
|
|
gptkbp:availableOn
|
gptkb:tablet
oral solution
|
|
gptkbp:bioavailability
|
almost 100%
|
|
gptkbp:brand
|
Levocet
Xyzal
|
|
gptkbp:CASNumber
|
130018-77-8
|
|
gptkbp:category
|
second-generation antihistamine
|
|
gptkbp:chemicalFormula
|
C21H25ClN2O3
|
|
gptkbp:contraindication
|
severe renal impairment
|
|
gptkbp:discoveredBy
|
gptkb:UCB_Pharma
|
|
gptkbp:eliminationHalfLife
|
8 to 9 hours
|
|
gptkbp:excretion
|
renal
|
|
gptkbp:hasEnantiomer
|
gptkb:cetirizine
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
levocetirizine
|
|
gptkbp:isomerOf
|
gptkb:cetirizine
|
|
gptkbp:KEGGID
|
D08123
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
H1 receptor antagonist
|
|
gptkbp:MedlinePlusID
|
a607054
|
|
gptkbp:metabolism
|
minimal hepatic
|
|
gptkbp:molecularWeight
|
388.89 g/mol
|
|
gptkbp:pregnancyCategory
|
B (US)
A (Australia)
|
|
gptkbp:prescribes
|
gptkb:hay_fever
hives
|
|
gptkbp:proteinBinding
|
90% to 92%
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL1201197
1549008
DB06282
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
fatigue
headache
drowsiness
dry mouth
|
|
gptkbp:UNII
|
44O0A3028G
|
|
gptkbp:usedFor
|
allergic rhinitis
chronic urticaria
|
|
gptkbp:bfsParent
|
gptkb:cetirizine
|
|
gptkbp:bfsLayer
|
6
|