Statements (24)
Predicate | Object |
---|---|
gptkbp:instanceOf |
integrin
|
gptkbp:alsoKnownAs |
gptkb:CD49d/CD29
gptkb:VLA-4 |
gptkbp:binds |
gptkb:fibronectin
gptkb:VCAM-1 |
gptkbp:category |
cell surface receptor
heterodimeric protein |
gptkbp:composedOf |
gptkb:integrin_alpha-4
gptkb:integrin_beta-1 |
gptkbp:encodedBy |
gptkb:ITGA4
gptkb:ITGB1 |
gptkbp:expressedIn |
gptkb:eosinophils
monocytes lymphocytes |
gptkbp:function |
cell adhesion
leukocyte migration |
https://www.w3.org/2000/01/rdf-schema#label |
alpha-4 beta-1 integrin
|
gptkbp:involvedIn |
gptkb:Crohn's_disease
multiple sclerosis inflammation immune response |
gptkbp:target |
gptkb:natalizumab
|
gptkbp:bfsParent |
gptkb:Tysabri
|
gptkbp:bfsLayer |
6
|