Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:abbreviation |
gptkb:EGF
|
| gptkbp:associatedWith |
gptkb:cancer
wound healing disorders |
| gptkbp:binds |
gptkb:epidermal_growth_factor_receptor
|
| gptkbp:category |
growth factor
signaling molecule |
| gptkbp:discoveredBy |
gptkb:Stanley_Cohen
|
| gptkbp:firstIsolatedFrom |
mouse submaxillary gland
|
| gptkbp:foundIn |
humans
mice other mammals |
| gptkbp:function |
stimulates cell growth
stimulates cell proliferation stimulates cell differentiation |
| gptkbp:gene |
gptkb:EGF_gene
|
| https://www.w3.org/2000/01/rdf-schema#label |
epidermal growth factor
|
| gptkbp:locatedOnChromosome |
chromosome 4q25 (human)
|
| gptkbp:molecularWeight |
~6 kDa
|
| gptkbp:NobelPrizeYear |
Nobel Prize in Physiology or Medicine 1986
|
| gptkbp:relatedTo |
gptkb:EGFR_signaling_pathway
|
| gptkbp:sequence |
53 amino acids (human)
|
| gptkbp:structure |
contains three disulfide bonds
|
| gptkbp:UniProtID |
P01133
|
| gptkbp:usedIn |
cancer research
cell culture wound healing research |
| gptkbp:bfsParent |
gptkb:EGFR
gptkb:P42338 |
| gptkbp:bfsLayer |
6
|