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gptkbp:instanceOf
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gptkb:protein
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gptkbp:abbreviation
|
gptkb:EGF
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gptkbp:associatedWith
|
gptkb:cancer
wound healing disorders
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gptkbp:binds
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gptkb:epidermal_growth_factor_receptor
|
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gptkbp:category
|
gptkb:growth_factor
gptkb:signaling_molecule
|
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gptkbp:discoveredBy
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gptkb:Stanley_Cohen
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gptkbp:firstIsolatedFrom
|
mouse submaxillary gland
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gptkbp:foundIn
|
humans
mice
other mammals
|
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gptkbp:function
|
stimulates cell growth
stimulates cell proliferation
stimulates cell differentiation
|
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gptkbp:gene
|
gptkb:EGF_gene
|
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gptkbp:locatedOnChromosome
|
chromosome 4q25 (human)
|
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gptkbp:molecularWeight
|
~6 kDa
|
|
gptkbp:NobelPrizeYear
|
Nobel Prize in Physiology or Medicine 1986
|
|
gptkbp:relatedTo
|
gptkb:EGFR_signaling_pathway
|
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gptkbp:sequence
|
53 amino acids (human)
|
|
gptkbp:structure
|
contains three disulfide bonds
|
|
gptkbp:UniProtID
|
P01133
|
|
gptkbp:usedIn
|
cancer research
cell culture
wound healing research
|
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gptkbp:bfsParent
|
gptkb:EGFR
gptkb:P00533
gptkb:P42338
gptkb:Heberprot-P
|
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gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
epidermal growth factor
|