|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:binds
|
gptkb:EGFR
|
|
gptkbp:category
|
growth factor
signaling molecule
mitogen
|
|
gptkbp:discoveredBy
|
gptkb:Stanley_Cohen
|
|
gptkbp:firstIsolatedFrom
|
mouse submaxillary glands
|
|
gptkbp:foundIn
|
humans
mice
other mammals
|
|
gptkbp:fullName
|
gptkb:Epidermal_Growth_Factor
|
|
gptkbp:function
|
stimulates cell growth
stimulates cell proliferation
stimulates cell differentiation
|
|
gptkbp:gene
|
gptkb:EGF_gene
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
EGF
|
|
gptkbp:inducedBy
|
signal transduction pathways
|
|
gptkbp:locatedOnChromosome
|
chromosome 4q25 (human)
|
|
gptkbp:molecularWeight
|
~6 kDa
|
|
gptkbp:NobelPrizeYear
|
Stanley Cohen received Nobel Prize in Physiology or Medicine in 1986
|
|
gptkbp:PDB
|
1JL9
|
|
gptkbp:promotion
|
epithelial cells
|
|
gptkbp:recipient
|
gptkb:EGFR
|
|
gptkbp:relatedTo
|
gptkb:transforming_growth_factor_alpha_(TGF-α)
gptkb:heparin-binding_EGF-like_growth_factor_(HB-EGF)
|
|
gptkbp:role
|
embryonic development
wound healing
cancer progression
|
|
gptkbp:sequence
|
53 amino acids
|
|
gptkbp:structure
|
single-chain polypeptide
|
|
gptkbp:UniProtID
|
P01133
|
|
gptkbp:usedIn
|
cell culture
cosmetic products
wound healing therapies
|
|
gptkbp:bfsParent
|
gptkb:American_Eagle_Airlines
gptkb:EGFR_signaling_pathway
gptkb:European_Go_Federation
|
|
gptkbp:bfsLayer
|
6
|