Statements (39)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
gptkb:cancer
neurodegenerative diseases |
| gptkbp:binds |
gptkb:gene
gptkb:eIF4E gptkb:eIF4A PABP |
| gptkbp:component |
eIF4F complex
|
| gptkbp:fullName |
Eukaryotic translation initiation factor 4 gamma
|
| gptkbp:function |
scaffold protein in translation initiation
|
| gptkbp:gene |
EIF4G1
EIF4G2 EIF4G3 |
| https://www.w3.org/2000/01/rdf-schema#label |
eIF4G
|
| gptkbp:interactsWith |
gptkb:eIF4B
Mnk1 eIF3 eIF4H |
| gptkbp:involvedIn |
cap-dependent translation
cap-independent translation |
| gptkbp:locale |
gptkb:cytoplasm
|
| gptkbp:molecularWeight |
~220 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologIn |
yeast TIF4631
yeast TIF4632 |
| gptkbp:PDB |
2VSO
|
| gptkbp:phosphorylates |
gptkb:S6K1
gptkb:mTOR |
| gptkbp:regulates |
translation efficiency
mRNA circularization |
| gptkbp:role |
translation initiation
|
| gptkbp:structure |
multi-domain
|
| gptkbp:UniProtID |
Q04637
Q8JZQ9 Q9Y6A9 |
| gptkbp:bfsParent |
gptkb:MNK1
gptkb:eIF4E |
| gptkbp:bfsLayer |
7
|