Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:database |
HGNC:3289
NCBI Gene:1975 UniProt:P23588 |
| gptkbp:fullName |
Eukaryotic translation initiation factor 4B
|
| gptkbp:function |
RNA binding
translation initiation stimulation of RNA helicase activity |
| gptkbp:gene |
EIF4B
|
| gptkbp:interactsWith |
gptkb:eIF4A
ribosome eIF3 |
| gptkbp:locale |
gptkb:cytoplasm
|
| gptkbp:locatedOnChromosome |
12q13
|
| gptkbp:molecularWeight |
80 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:pathway |
gptkb:mTOR_signaling_pathway
translation initiation |
| gptkbp:phosphorylates |
regulated by RSK
regulated by S6K |
| gptkbp:regulates |
phosphorylation-dependent
|
| gptkbp:sequence |
UniProt:P23588
|
| gptkbp:significance |
overexpressed in some cancers
|
| gptkbp:species |
gptkb:human
gptkb:mouse gptkb:yeast |
| gptkbp:structure |
contains RNA recognition motif
contains arginine-rich region |
| gptkbp:bfsParent |
gptkb:Ribosomal_protein_S6_kinase
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
eIF4B
|