cytochrome P450 family 1 subfamily A member 2

URI: https://gptkb.org/entity/cytochrome_P450_family_1_subfamily_A_member_2
GPTKB entity
Statements (49)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:enzyme
gptkbp:alternativeName gptkb:CYP1A2
gptkb:P450DB1
gptkb:cytochrome_P450_1A2
gptkbp:EC_number 1.14.14.1
gptkbp:encodedBy CYP1A2 gene
gptkbp:Entrez_Gene_ID gptkb:CYP1A2
gptkbp:expressedIn gptkb:cancer
liver
gptkbp:family gptkb:cytochrome_P450
gptkbp:function drug metabolism
xenobiotic metabolism
caffeine metabolism
metabolism of polycyclic aromatic hydrocarbons
gptkbp:HGNC_ID 2596
https://www.w3.org/2000/01/rdf-schema#label cytochrome P450 family 1 subfamily A member 2
gptkbp:inducedBy gptkb:tobacco_smoke
gptkb:omeprazole
cruciferous vegetables
gptkbp:inhibitedBy gptkb:fluvoxamine
cimetidine
ciprofloxacin
gptkbp:locatedIn gptkb:endoplasmic_reticulum
gptkbp:locatedOnChromosome chromosome 15q24.1
gptkbp:member 2
gptkbp:molecularWeight 58 kDa
gptkbp:OMIM 124060
gptkbp:organism gptkb:Homo_sapiens
gptkbp:pathway drug metabolism - cytochrome P450
metabolism of xenobiotics by cytochrome P450
chemical carcinogenesis
gptkbp:PDB 2HI4
2J0D
2J0M
2J0N
2J0P
gptkbp:product gptkb:CYP1A2
gptkbp:RefSeq NP_000755.2
gptkbp:subfamily 1A
gptkbp:substrate gptkb:theophylline
gptkb:tacrine
gptkb:clozapine
caffeine
acetaminophen
phenacetin
gptkbp:UniProtID gptkb:P05177
gptkbp:bfsParent gptkb:CYP1A2
gptkbp:bfsLayer 5