cyclin dependent kinase 2

URI: https://gptkb.org/entity/cyclin_dependent_kinase_2
GPTKB entity
Statements (38)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:enzyme
gptkbp:alternativeName gptkb:cell_division_protein_kinase_2
gptkb:CDK2
gptkbp:EC_number 2.7.11.22
gptkbp:Entrez_Gene_ID gptkb:CDK2
gptkbp:expressedIn many tissues
gptkbp:function cell cycle regulation
phosphorylation of target proteins
gptkbp:HGNC_ID 1771
gptkbp:inhibitedBy gptkb:p21
gptkb:p27
gptkb:roscovitine
gptkbp:interactsWith gptkb:cyclin_A
gptkb:cyclin_E
gptkbp:involves gptkb:G1/S_transition
S phase progression
gptkbp:locatedIn gptkb:nucleus
gptkbp:locatedOnChromosome 12q13
gptkbp:molecularWeight 33 kDa
gptkbp:OMIM 116946
gptkbp:organism gptkb:Homo_sapiens
gptkbp:PDB 1FIN
gptkbp:phosphorylates gptkb:RB1
gptkb:NPAT
gptkb:p53
gptkbp:product gptkb:CDK2_gene
gptkbp:requires cell proliferation
DNA replication
gptkbp:UniProtID P24941
gptkbp:bfsParent gptkb:HGNC:1633
gptkb:HGNC:1704
gptkb:hsa:983
gptkb:HGNC:1014
gptkb:HGNC:1588
gptkb:HGNC:1709
gptkbp:bfsLayer 8
https://www.w3.org/2000/01/rdf-schema#label cyclin dependent kinase 2