Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:alternativeName |
gptkb:cell_division_protein_kinase_2
gptkb:CDK2 |
| gptkbp:EC_number |
2.7.11.22
|
| gptkbp:Entrez_Gene_ID |
gptkb:CDK2
|
| gptkbp:expressedIn |
many tissues
|
| gptkbp:function |
cell cycle regulation
phosphorylation of target proteins |
| gptkbp:HGNC_ID |
1771
|
| https://www.w3.org/2000/01/rdf-schema#label |
cyclin dependent kinase 2
|
| gptkbp:inhibitedBy |
gptkb:p21
gptkb:p27 gptkb:roscovitine |
| gptkbp:interactsWith |
gptkb:cyclin_A
gptkb:cyclin_E |
| gptkbp:involves |
gptkb:G1/S_transition
S phase progression |
| gptkbp:locatedIn |
gptkb:nucleus
|
| gptkbp:locatedOnChromosome |
12q13
|
| gptkbp:molecularWeight |
33 kDa
|
| gptkbp:OMIM |
116946
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:PDB |
1FIN
|
| gptkbp:phosphorylates |
gptkb:RB1
gptkb:NPAT gptkb:p53 |
| gptkbp:product |
gptkb:CDK2_gene
|
| gptkbp:requires |
cell proliferation
DNA replication |
| gptkbp:UniProtID |
P24941
|
| gptkbp:bfsParent |
gptkb:HGNC:1633
|
| gptkbp:bfsLayer |
7
|