|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:RNF55
Casitas B-lineage lymphoma
Cbl proto-oncogene
|
|
gptkbp:alternativeSplicing
|
CBL-b
CBL-c
|
|
gptkbp:discoveredBy
|
gptkb:Hidesaburo_Hanafusa
|
|
gptkbp:discoveredIn
|
1989
|
|
gptkbp:domain
|
SH2 domain
RING finger domain
proline-rich region
|
|
gptkbp:encodedBy
|
gptkb:CBL_gene
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
gptkb:E3_ubiquitin-protein_ligase
|
|
gptkbp:HGNC_ID
|
1541
|
|
gptkbp:interactsWith
|
gptkb:EGFR
gptkb:Src
gptkb:PI3K
gptkb:Grb2
gptkb:ZAP-70
|
|
gptkbp:involvedIn
|
signal transduction
protein ubiquitination
|
|
gptkbp:locale
|
gptkb:cytoplasm
gptkb:plasma_membrane
|
|
gptkbp:locatedOnChromosome
|
11q23.3
|
|
gptkbp:mutationAssociatedWith
|
gptkb:leukemia
gptkb:juvenile_myelomonocytic_leukemia
myelodysplastic syndromes
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:phosphorylates
|
tyrosine kinases
|
|
gptkbp:regulates
|
tyrosine kinase signaling
|
|
gptkbp:UniProtID
|
P22681
|
|
gptkbp:bfsParent
|
gptkb:Sprouty2
gptkb:SH2B2
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
c-Cbl
|