|
gptkbp:instanceOf
|
gptkb:non-coding_RNA
|
|
gptkbp:associatedWith
|
Barr body formation
|
|
gptkbp:compatibleWith
|
male cells
|
|
gptkbp:discoveredBy
|
gptkb:Carolyn_J._Brown
gptkb:Harold_Willard
|
|
gptkbp:discoveredIn
|
1991
|
|
gptkbp:encodedBy
|
gptkb:XIST_gene
|
|
gptkbp:enemyOf
|
gptkb:Tsix_RNA
|
|
gptkbp:expressedIn
|
female cells
|
|
gptkbp:foundIn
|
eutherian mammals
|
|
gptkbp:function
|
gptkb:X-chromosome_inactivation
|
|
gptkbp:involves
|
gptkb:Klinefelter_syndrome
gptkb:Turner_syndrome
X chromosome aneuploidies
|
|
gptkbp:isTranscribedFrom
|
inactive X chromosome
|
|
gptkbp:length
|
~17,000 nucleotides (human)
|
|
gptkbp:locale
|
inactive X chromosome
|
|
gptkbp:locatedOnChromosome
|
gptkb:X_chromosome
|
|
gptkbp:mechanismOfAction
|
coats X chromosome in cis
|
|
gptkbp:orthologIn
|
gptkb:Xist_(mouse)
|
|
gptkbp:recruitedFrom
|
gptkb:Polycomb_repressive_complex_2
gptkb:hnRNP_U
gptkb:SMRT/HDAC1-associated_repressor_protein
gptkb:SPEN_protein
|
|
gptkbp:regulates
|
gptkb:YY1
gptkb:Rex1
gptkb:Sox2
gptkb:Nanog
gptkb:Oct4
gptkb:CTCF
gptkb:Ftx_RNA
gptkb:Jpx_RNA
gptkb:PRC2
gptkb:RNF12
gptkb:Tsix
gptkb:X-inactivation_center
DNA methylation
histone modifications
chromatin state
enhancers
Xist promoter
cis-regulatory elements
gene dosage compensation
pluripotency factors
repressors
trans-acting factors
|
|
gptkbp:relatedTo
|
gptkb:X-inactivation_center
|
|
gptkbp:studiedIn
|
developmental biology
|
|
gptkbp:bfsParent
|
gptkb:RSX_family
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Xist RNA
|