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gptkbp:instanceOf
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gptkb:gene
|
|
gptkbp:alias
|
XIST
XIST lncRNA
inactive X specific transcripts
|
|
gptkbp:associatedWith
|
gptkb:Klinefelter_syndrome
gptkb:Turner_syndrome
X-linked diseases
FTX gene
JPX gene
RNF12 gene
SMCHD1 gene
TSIX gene
X chromosome inactivation center
|
|
gptkbp:biologicalProcess
|
gene silencing
chromatin modification
epigenetic regulation
RNA binding
dosage compensation
|
|
gptkbp:category
|
epigenetic regulator
lncRNA gene
|
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gptkbp:compatibleWith
|
male cells
|
|
gptkbp:conservedIn
|
mammals
|
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gptkbp:discoveredBy
|
gptkb:Carolyn_J._Brown
|
|
gptkbp:discoveredIn
|
1991
|
|
gptkbp:Entrez_Gene_ID
|
7503
ENSG00000229807
|
|
gptkbp:expressedIn
|
female cells
monoallelic
|
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gptkbp:fullName
|
X-inactive specific transcript
|
|
gptkbp:function
|
X chromosome inactivation
|
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gptkbp:geneType
|
non-coding RNA
|
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gptkbp:hasTranscript
|
gptkb:XIST_RNA
|
|
gptkbp:HGNC_ID
|
12810
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
XIST gene
|
|
gptkbp:length
|
~17 kb (human)
|
|
gptkbp:locatedOnChromosome
|
gptkb:X_chromosome
|
|
gptkbp:methylationStatus
|
differentially methylated
|
|
gptkbp:OMIM
|
314670
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Xist_gene
|
|
gptkbp:RefSeq
|
NR_001564
|
|
gptkbp:regulates
|
regulated by FTX
regulated by JPX
regulated by RNF12
regulated by TSIX
regulated by pluripotency factors
silencing of X chromosome
upregulated in early embryogenesis
|
|
gptkbp:significance
|
aberrant expression linked to X-linked disorders
|
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gptkbp:subcellularLocation
|
gptkb:nucleus
Barr body
|
|
gptkbp:transcriptionDirection
|
antisense to TSIX gene
|
|
gptkbp:transcriptLength
|
~19 kb (human)
|
|
gptkbp:bfsParent
|
gptkb:XIST_RNA
gptkb:NR_002728
gptkb:Xist_RNA
gptkb:X-inactivation
gptkb:X-chromosome_inactivation
|
|
gptkbp:bfsLayer
|
8
|