Properties (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic disorder
|
| gptkbp:associatedWith |
anemia
anxiety depression increased risk of cardiovascular disease learning disabilities chronic fatigue learning difficulties varicose veins social difficulties increased risk of diabetes infertility issues hypogonadism decreased libido gynecomastia thinning hair increased risk of certain cancers increased risk of obesity delayed speech development increased risk of autoimmune diseases increased risk of infertility increased risk of lung disease increased risk of metabolic disorders increased risk of psychiatric disorders testicular atrophy |
| gptkbp:causedBy |
extra X chromosome
|
| gptkbp:complications |
metabolic syndrome
breast cancer osteoporosis type 2 diabetes autoimmune disorders |
| gptkbp:demographics |
1 in 500 to 1 in 1,000 males
|
| gptkbp:diseaseResistance |
karyotype analysis
|
| gptkbp:firstDescribedBy |
gptkb:Harry_Klinefelter
|
| gptkbp:geneticDiversity |
47,XXY
non-Mendelian_inheritance |
| https://www.w3.org/2000/01/rdf-schema#label |
Klinefelter syndrome
|
| gptkbp:impact |
males
fertility treatment testosterone replacement therapy |
| gptkbp:legalEvent |
normal life expectancy
|
| gptkbp:locatedIn |
1942
|
| gptkbp:riskManagement |
family history
advanced maternal age |
| gptkbp:screenings |
prenatal testing
newborn screening |
| gptkbp:symptoms |
infertility
tall stature breast tissue development reduced testosterone |