Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic disorder
syndrome |
| gptkbp:affects |
males
|
| gptkbp:causedBy |
extra X chromosome
|
| gptkbp:chromosomePattern |
47,XXY
|
| gptkbp:complication |
gptkb:cancer
gptkb:bone autoimmune disorders |
| gptkbp:diagnosedBy |
karyotype analysis
|
| gptkbp:firstDescribed |
1942
Harry Klinefelter |
| gptkbp:frequency |
common sex chromosome aneuploidy in males
|
| https://www.w3.org/2000/01/rdf-schema#label |
Klinefelter syndrome
|
| gptkbp:ICD-10_code |
gptkb:Q98
|
| gptkbp:inheritance |
not inherited (usually random event)
|
| gptkbp:MeSH_ID |
D007713
|
| gptkbp:OMIM |
400047
|
| gptkbp:prevalence |
1 in 500 to 1 in 1,000 male births
|
| gptkbp:riskFactor |
advanced maternal age
|
| gptkbp:symptom |
infertility
tall stature gynecomastia learning difficulties small testes reduced facial hair |
| gptkbp:synonym |
47,XXY syndrome
XXY syndrome |
| gptkbp:treatment |
fertility treatment
testosterone replacement therapy |
| gptkbp:bfsParent |
gptkb:Meiosis
|
| gptkbp:bfsLayer |
6
|