Tsix RNA

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:gene
non-coding RNA
gptkbp:amendedBy chromatin structure
gptkbp:antisenseTo gptkb:Xist_RNA
gptkbp:associatedWith epigenetic regulation
gptkbp:discoveredIn 1999
gptkbp:expressedIn early embryogenesis
gptkbp:foundIn gptkb:mouse
mammals
gptkbp:function maintains active X chromosome
represses Xist expression
https://www.w3.org/2000/01/rdf-schema#label Tsix RNA
gptkbp:involvedIn gptkb:X-chromosome_inactivation
gptkbp:isTranscribedFrom Xist locus
gptkbp:length ~40 kb
gptkbp:locatedOn gptkb:X_chromosome
gptkbp:orthologIn TSIX (truncated, non-functional)
gptkbp:regulates gptkb:Xist_RNA
DNA methylation at Xist promoter
gptkbp:requires imprinted X inactivation in extraembryonic tissues
gptkbp:transcriptionDirection opposite to Xist
gptkbp:bfsParent gptkb:Xist_RNA
gptkbp:bfsLayer 8