|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:IRP
INT1-related protein
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:autism_spectrum_disorder
cell differentiation
cell proliferation
colorectal cancer
gastric cancer
oncogenesis
|
|
gptkbp:biologicalProcess
|
signaling molecule
|
|
gptkbp:component
|
extracellular region
|
|
gptkbp:discoveredBy
|
gptkb:Nusse_and_Varmus
|
|
gptkbp:discoveredIn
|
1982
|
|
gptkbp:encodes
|
Wnt-2 protein
|
|
gptkbp:Entrez_Gene_ID
|
7472
ENSG00000105989
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:placenta
brain
colon
organogenesis
embryogenesis
|
|
gptkbp:function
|
Wnt-protein binding
|
|
gptkbp:GOProcess
|
canonical Wnt signaling pathway
|
|
gptkbp:HGNC_ID
|
12783
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
WNT2 gene
|
|
gptkbp:interactsWith
|
gptkb:Frizzled_receptors
gptkb:LRP5/6_co-receptors
|
|
gptkbp:involvedIn
|
gptkb:Wnt_signaling_pathway
|
|
gptkbp:length
|
360 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_7
7q31.2
|
|
gptkbp:memberOf
|
gptkb:WNT_gene_family
|
|
gptkbp:mutationAssociatedWith
|
cancer progression
developmental disorders
|
|
gptkbp:OMIM
|
147870
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Wnt2
|
|
gptkbp:product
|
gptkb:Wnt-2
|
|
gptkbp:proteinFamily
|
gptkb:Wnt_family
|
|
gptkbp:RefSeq
|
NM_003391
|
|
gptkbp:regulates
|
embryonic development
gene expression
cell migration
cell fate determination
cell polarity
|
|
gptkbp:target
|
beta-catenin/TCF signaling
|
|
gptkbp:UniProtID
|
P09544
|
|
gptkbp:bfsParent
|
gptkb:Wnt-2
gptkb:Wnt2
gptkb:Wnt_family_member_2_protein
|
|
gptkbp:bfsLayer
|
8
|