|
gptkbp:instanceOf
|
gptkb:receptor_tyrosine_kinase
gptkb:protein
|
|
gptkbp:activatedBy
|
gptkb:neurotrophin-3
|
|
gptkbp:alternativeName
|
Neurotrophic tyrosine kinase receptor type 3
|
|
gptkbp:binds
|
gptkb:neurotrophin-3
|
|
gptkbp:discoveredIn
|
1991
|
|
gptkbp:domain
|
immunoglobulin-like domain
tyrosine kinase domain
|
|
gptkbp:downstreamOf
|
gptkb:MAPK_pathway
gptkb:PLCĪ³_pathway
gptkb:PI3K-Akt_pathway
|
|
gptkbp:EC_number
|
2.7.10.1
|
|
gptkbp:encodedBy
|
gptkb:NTRK3_gene
|
|
gptkbp:expressedIn
|
gptkb:nervous_system
brain
peripheral nervous system
|
|
gptkbp:function
|
neurotrophin receptor
|
|
gptkbp:hasBiologicalActivity
|
gptkb:receptor_tyrosine_kinase
|
|
gptkbp:HGNC_ID
|
8032
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TrkC receptor
|
|
gptkbp:involvedIn
|
cell differentiation
cell survival
signal transduction
neuronal development
|
|
gptkbp:locatedIn
|
gptkb:cell_membrane
|
|
gptkbp:memberOf
|
gptkb:Trk_receptor_family
|
|
gptkbp:molecularWeight
|
~145 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
gptkb:congenital_insensitivity_to_pain
|
|
gptkbp:orthologIn
|
gptkb:mouse
gptkb:zebrafish
right
|
|
gptkbp:PDB
|
gptkb:4AT3
|
|
gptkbp:UniProtID
|
Q16288
|
|
gptkbp:bfsParent
|
gptkb:NTF3_protein
gptkb:Neurotrophin-3
|
|
gptkbp:bfsLayer
|
8
|