|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:binds
|
gptkb:neurotrophin-3
|
|
gptkbp:encodedBy
|
gptkb:NTRK3_gene
|
|
gptkbp:Entrez_Gene_ID
|
4915
ENSG00000140538
|
|
gptkbp:expressedIn
|
brain
peripheral nervous system
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
gptkb:receptor_tyrosine_kinase
|
|
gptkbp:hasIsoform
|
gptkb:TrkC_full-length
gptkb:TrkC_truncated
|
|
gptkbp:HGNC_ID
|
8032
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TrkC
|
|
gptkbp:involvedIn
|
cell survival
nervous system development
neuronal differentiation
|
|
gptkbp:ligand
|
gptkb:neurotrophin-3
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_15q25
|
|
gptkbp:memberOf
|
gptkb:Trk_receptor_family
|
|
gptkbp:molecularWeight
|
~145 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
gptkb:congenital_insensitivity_to_pain
|
|
gptkbp:OMIM
|
191316
|
|
gptkbp:PDB
|
gptkb:1WWW
|
|
gptkbp:phosphorylates
|
tyrosine residues
|
|
gptkbp:type
|
gptkb:MAPK_pathway
gptkb:PLCĪ³_pathway
gptkb:PI3K-Akt_pathway
|
|
gptkbp:UniProtID
|
Q16288
|
|
gptkbp:bfsParent
|
gptkb:Networker_3_(NTK3)
|
|
gptkbp:bfsLayer
|
6
|