|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:TGF-beta1
gptkb:Cedar
gptkb:TGFB
D4Ertd654e
|
|
gptkbp:associatedWith
|
gptkb:cancer
inflammation
fibrosis
|
|
gptkbp:discoveredIn
|
1983
|
|
gptkbp:encodes
|
TGF-beta 1 protein
|
|
gptkbp:Entrez_Gene_ID
|
21803
ENSMUSG00000021253
|
|
gptkbp:expressedIn
|
many tissues
|
|
gptkbp:fullName
|
transforming growth factor beta 1
|
|
gptkbp:function
|
regulation of cell differentiation
regulation of cell growth
extracellular matrix production
immune system modulation
|
|
gptkbp:interactsWith
|
gptkb:SMAD2
gptkb:SMAD3
gptkb:TGFBR2
gptkb:TGFBR1
gptkb:SMAD4
|
|
gptkbp:length
|
391 amino acids
|
|
gptkbp:locatedOnChromosome
|
7
|
|
gptkbp:location
|
7 F5
|
|
gptkbp:mainTerminal
|
GO:0005615 (extracellular space)
GO:0008285 (negative regulation of cell proliferation)
GO:0006954 (inflammatory response)
GO:0007179 (transforming growth factor beta receptor signaling pathway)
|
|
gptkbp:mgiID
|
MGI:98787
|
|
gptkbp:molecularWeight
|
44 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:inflammatory_bowel_disease
developmental defects
impaired immune response
|
|
gptkbp:organism
|
gptkb:Mus_musculus
|
|
gptkbp:orthologIn
|
TGFB1 (human)
|
|
gptkbp:pathway
|
gptkb:TGF-beta_signaling_pathway
|
|
gptkbp:proteinFamily
|
gptkb:TGF-beta_superfamily
|
|
gptkbp:regulates
|
gptkb:immune_response
apoptosis
cell proliferation
wound healing
angiogenesis
extracellular matrix organization
|
|
gptkbp:UniProtID
|
P04202
|
|
gptkbp:bfsParent
|
gptkb:chromosome_7_(mouse)
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Tgfb1
|