|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:CD288
|
|
gptkbp:associatedWith
|
autoimmune diseases
viral infection response
|
|
gptkbp:biologicalProcess
|
pattern recognition receptor
|
|
gptkbp:discoveredIn
|
2001
|
|
gptkbp:encodes
|
Toll-like receptor 8 protein
|
|
gptkbp:Entrez_Gene_ID
|
51311
ENSG00000104814
|
|
gptkbp:expressedIn
|
dendritic cells
macrophages
monocytes
|
|
gptkbp:family
|
gptkb:Toll-like_receptor_family
|
|
gptkbp:fullName
|
gptkb:Toll-like_receptor_8
|
|
gptkbp:function
|
innate immune response
recognition of single-stranded RNA
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GO_term
|
GO:0002224
GO:0002755
GO:0034138
|
|
gptkbp:HGNC_ID
|
18049
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TLR8
|
|
gptkbp:interactsWith
|
gptkb:IRAK4
MYD88
UNC93B1
|
|
gptkbp:length
|
1041
|
|
gptkbp:ligand
|
single-stranded RNA
imidazoquinoline compounds
|
|
gptkbp:locatedOnChromosome
|
X
Xq11.2
|
|
gptkbp:location
|
gptkb:endosome
|
|
gptkbp:mutationAssociatedWith
|
gptkb:systemic_lupus_erythematosus
asthma
rheumatoid arthritis
|
|
gptkbp:OMIM
|
300063
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Tlr8
|
|
gptkbp:pathway
|
gptkb:Toll-like_receptor_signaling_pathway
|
|
gptkbp:proteinFamily
|
leucine-rich repeat
TIR domain
|
|
gptkbp:RefSeq
|
NM_138636
|
|
gptkbp:relatedTo
|
gptkb:TLR3
gptkb:TLR9
TLR7
|
|
gptkbp:species
|
gptkb:human
|
|
gptkbp:UniProtID
|
gptkb:Q9NR97
|
|
gptkbp:bfsParent
|
gptkb:Toll-like_receptors
|
|
gptkbp:bfsLayer
|
7
|