Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:associatedWith |
gptkb:Loeys-Dietz_syndrome
gptkb:cancer gptkb:Marfan_syndrome |
| gptkbp:biologicalProcess |
serine/threonine kinase activity
|
| gptkbp:component |
gptkb:TGF-beta_receptor_type_I
gptkb:TGF-beta_receptor_type_II gptkb:TGF-beta_receptor_type_III |
| gptkbp:discoveredBy |
1980s
|
| gptkbp:function |
binds TGF-beta ligands
initiates TGF-beta signaling pathway |
| gptkbp:gene |
gptkb:TGFBR2
gptkb:TGFBR1 gptkb:TGFBR3 |
| https://www.w3.org/2000/01/rdf-schema#label |
TGF-beta receptor
|
| gptkbp:ligand |
gptkb:TGF-beta1
gptkb:TGF-beta2 gptkb:TGF-beta3 |
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:pathway |
SMAD signaling pathway
|
| gptkbp:relatedTo |
apoptosis
differentiation immune response cell growth regulation |
| gptkbp:species |
gptkb:human
gptkb:mouse gptkb:zebrafish |
| gptkbp:bfsParent |
gptkb:NEDD4-1
|
| gptkbp:bfsLayer |
6
|