Suppressor of Cytokine Signaling
GPTKB entity
Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:abbreviation |
gptkb:SOCS
|
| gptkbp:discoveredBy |
gptkb:Douglas_J._Hilton
1997 |
| gptkbp:domain |
gptkb:SOCS_box
SH2 domain |
| gptkbp:encodedBy |
SOCS genes
|
| gptkbp:foundIn |
mammals
|
| gptkbp:function |
negative regulation of cytokine signaling
|
| gptkbp:hasMember |
gptkb:SOCS1
gptkb:SOCS2 gptkb:SOCS3 gptkb:SOCS4 gptkb:SOCS5 gptkb:SOCS6 gptkb:SOCS7 gptkb:CIS |
| https://www.w3.org/2000/01/rdf-schema#label |
Suppressor of Cytokine Signaling
|
| gptkbp:inhibitedBy |
gptkb:STAT_proteins
gptkb:JAK_kinases cytokine signaling |
| gptkbp:regulates |
gptkb:JAK-STAT_signaling_pathway
inflammation immune response |
| gptkbp:relatedTo |
gptkb:cancer
autoimmune diseases inflammatory diseases |
| gptkbp:bfsParent |
gptkb:SOCS
|
| gptkbp:bfsLayer |
7
|