Statements (36)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:associatedWith |
apoptosis
tumor suppression insulin signaling |
| gptkbp:chromosomeArm |
18q22.2
|
| gptkbp:domain |
gptkb:SOCS_box
SH2 domain |
| gptkbp:encodes |
SOCS6 protein
|
| gptkbp:Entrez_Gene_ID |
9306
|
| gptkbp:expressedIn |
various tissues
|
| gptkbp:fullName |
Suppressor of cytokine signaling 6
|
| gptkbp:function |
negative regulation of cytokine signaling
inhibition of JAK/STAT pathway |
| gptkbp:HGNC_ID |
HGNC:19397
|
| https://www.w3.org/2000/01/rdf-schema#label |
SOCS6
|
| gptkbp:interactsWith |
gptkb:JAK2
gptkb:insulin_receptor gptkb:IRS1 gptkb:c-Kit |
| gptkbp:locatedOnChromosome |
18
|
| gptkbp:mutationAssociatedWith |
gptkb:cancer
gptkb:diabetes |
| gptkbp:OMIM |
604260
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
Socs6
|
| gptkbp:proteinFamily |
gptkb:SOCS_family
|
| gptkbp:regulates |
apoptosis
cell differentiation cell growth insulin receptor signaling |
| gptkbp:UniProtID |
O14544
|
| gptkbp:bfsParent |
gptkb:SOCS
gptkb:SOCS_family gptkb:SOCS_proteins gptkb:Cish_(mouse_gene) |
| gptkbp:bfsLayer |
7
|