Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:G_protein-coupled_receptor |
| gptkbp:activatedBy |
Hedgehog ligand (indirectly)
|
| gptkbp:associatedWith |
gptkb:cancer
|
| gptkbp:encodedBy |
SMO gene
|
| gptkbp:Entrez_Gene_ID |
6608
|
| gptkbp:foundIn |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:function |
signal transduction
|
| https://www.w3.org/2000/01/rdf-schema#label |
Smoothened receptor
|
| gptkbp:inhibitedBy |
gptkb:Patched_receptor
|
| gptkbp:involvedIn |
gptkb:Hedgehog_signaling_pathway
|
| gptkbp:locatedOnChromosome |
7q32.1
|
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:OMIM |
601500
|
| gptkbp:regulates |
gptkb:GLI_transcription_factors
|
| gptkbp:structure |
seven transmembrane domains
|
| gptkbp:target |
gptkb:sonidegib
gptkb:vismodegib glasdegib |
| gptkbp:UniProtID |
Q99835
|
| gptkbp:bfsParent |
gptkb:Class_F_(Frizzled/Taste2)
|
| gptkbp:bfsLayer |
6
|