Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
hedgehog pathway inhibitor |
| gptkbp:approvalYear |
2015
|
| gptkbp:approvedBy |
gptkb:FDA
gptkb:EMA |
| gptkbp:ATCCode |
L01XX54
|
| gptkbp:brand |
gptkb:Odomzo
|
| gptkbp:CASNumber |
956104-40-8
|
| gptkbp:chemicalClass |
pyridine derivative
|
| gptkbp:developer |
gptkb:Novartis
|
| gptkbp:hasMolecularFormula |
C26H26N4O3
|
| https://www.w3.org/2000/01/rdf-schema#label |
sonidegib
|
| gptkbp:indication |
locally advanced basal cell carcinoma
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
smoothened receptor antagonist
|
| gptkbp:pregnancyCategory |
D (US)
|
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
nausea
fatigue alopecia dysgeusia muscle spasms |
| gptkbp:synonym |
LDE225
|
| gptkbp:target |
SMO protein
|
| gptkbp:UNII |
8KQ660G10Z
|
| gptkbp:usedFor |
treatment of basal cell carcinoma
|
| gptkbp:bfsParent |
gptkb:Odomzo
gptkb:Hedgehog_signaling_pathway gptkb:Smoothened_receptor |
| gptkbp:bfsLayer |
7
|