Statements (35)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:drug
small molecule |
gptkbp:administeredBy |
oral
|
gptkbp:approvedBy |
gptkb:FDA
2012 |
gptkbp:ATCCode |
gptkb:L01XX43
|
gptkbp:brand |
gptkb:Erivedge
|
gptkbp:CASNumber |
879085-55-9
|
gptkbp:contraindication |
pregnancy
|
gptkbp:developedBy |
gptkb:Genentech
gptkb:Roche |
gptkbp:hasMolecularFormula |
C19H14Cl2N2O3S
|
https://www.w3.org/2000/01/rdf-schema#label |
vismodegib
|
gptkbp:KEGGID |
D09722
|
gptkbp:legalStatus |
prescription only
|
gptkbp:mechanismOfAction |
Hedgehog pathway inhibitor
|
gptkbp:pregnancyCategory |
D (US)
|
gptkbp:PubChem_CID |
24776410
CHEMBL1229518 DB08816 |
gptkbp:routeOfAdministration |
oral
|
gptkbp:sideEffect |
nausea
fatigue weight loss alopecia dysgeusia muscle spasms |
gptkbp:synonym |
gptkb:GDC-0449
|
gptkbp:target |
gptkb:Smoothened_(SMO)_receptor
|
gptkbp:UNII |
YOP970Q0FS
|
gptkbp:usedFor |
treatment of basal cell carcinoma
|
gptkbp:bfsParent |
gptkb:Erivedge
gptkb:Hedgehog_signaling_pathway gptkb:Smoothened_receptor |
gptkbp:bfsLayer |
7
|