|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
neuronal development
cardiac development
smooth muscle cell differentiation
|
|
gptkbp:chromosomeArm
|
gptkb:6p21.1
|
|
gptkbp:discoveredBy
|
1988
|
|
gptkbp:encodes
|
Serum response factor protein
|
|
gptkbp:Entrez_Gene_ID
|
6722
ENSG00000112658
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:skeletal_muscle
gptkb:kidney
gptkb:testis
brain
heart
liver
smooth muscle
|
|
gptkbp:fullName
|
Serum Response Factor
|
|
gptkbp:function
|
gptkb:transcription_factor
binds serum response element (SRE)
regulates immediate-early genes
|
|
gptkbp:HGNC_ID
|
11291
|
|
gptkbp:interactsWith
|
gptkb:ELK1
gptkb:MRTF-A
gptkb:MRTF-B
TCF family proteins
|
|
gptkbp:involvedIn
|
cell growth
muscle differentiation
cytoskeletal gene regulation
|
|
gptkbp:locatedOnChromosome
|
6
|
|
gptkbp:mutationAssociatedWith
|
gptkb:muscular_dystrophy
gptkb:cardiomyopathy
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Srf
|
|
gptkbp:proteinFamily
|
gptkb:MADS-box
|
|
gptkbp:regulates
|
gptkb:FOS_gene
gptkb:RhoA_signaling_pathway
gptkb:MAPK_signaling_pathway
gptkb:EGR1_gene
gptkb:c-fos_gene
gptkb:serum_response_element_(SRE)
gptkb:ACTA1_gene
phosphorylation
calcium signaling pathway
muscle-specific genes
VCL gene
|
|
gptkbp:UniProtID
|
P11831
|
|
gptkbp:bfsParent
|
gptkb:Serum_response_factor
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SRF gene
|