Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:BSAC
MAL MKL1 |
| gptkbp:associatedWith |
acute megakaryoblastic leukemia (when fused with RBM15)
|
| gptkbp:domain |
gptkb:SAP_domain
Leucine zipper domain RPEL domain |
| gptkbp:encodedBy |
MKL1 gene
|
| gptkbp:fullName |
Myocardin-related transcription factor A
|
| gptkbp:function |
transcriptional coactivator
regulates SRF-dependent gene expression |
| gptkbp:gene |
MKL1
|
| https://www.w3.org/2000/01/rdf-schema#label |
MRTF-A
|
| gptkbp:interactsWith |
Serum Response Factor (SRF)
|
| gptkbp:locale |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:locatedOnChromosome |
gptkb:22q13.1
|
| gptkbp:orthologIn |
gptkb:mouse
gptkb:zebrafish right |
| gptkbp:phosphorylates |
regulates nuclear localization
|
| gptkbp:regulates |
actin cytoskeleton dynamics
regulated by Rho GTPases regulated by actin polymerization |
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:UniProtID |
Q969V6
|
| gptkbp:bfsParent |
gptkb:Serum_response_factor
|
| gptkbp:bfsLayer |
7
|