Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
transcription factor |
| gptkbp:biologicalProcess |
DNA binding
transcriptional activator activity |
| gptkbp:domain |
MADS-box domain
|
| gptkbp:encodedBy |
gptkb:SRF_gene
|
| gptkbp:Entrez_Gene_ID |
gptkb:SRF
ENSG00000112658 |
| gptkbp:foundIn |
gptkb:Mus_musculus
gptkb:Homo_sapiens gptkb:Rattus_norvegicus |
| gptkbp:function |
regulation of gene expression
binds serum response element |
| gptkbp:gene |
gptkb:SRF
|
| gptkbp:HGNC_ID |
11291
|
| https://www.w3.org/2000/01/rdf-schema#label |
Serum response factor
|
| gptkbp:interactsWith |
gptkb:ELK1
gptkb:MRTF-A gptkb:MRTF-B TCF proteins |
| gptkbp:locatedIn |
gptkb:nucleus
|
| gptkbp:locatedOnChromosome |
6p21.1 (human)
|
| gptkbp:OMIM |
600589
|
| gptkbp:part_of |
MADS-box protein family
|
| gptkbp:regulates |
gptkb:synaptic_plasticity
gptkb:c-fos_gene apoptosis cell differentiation wound healing angiogenesis cell growth cell migration neuronal development neurite outgrowth learning and memory cellular response to growth factors inflammatory response tumorigenesis fibrosis muscle development cardiac development immediate early genes cardiac hypertrophy actin cytoskeleton genes cytoskeletal gene expression muscle-specific genes smooth muscle cell differentiation vascular smooth muscle cell proliferation |
| gptkbp:UniProtID |
P11831
|
| gptkbp:bfsParent |
gptkb:SRF
|
| gptkbp:bfsLayer |
6
|