|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:activatedBy
|
gptkb:PI3K_pathway
gptkb:glucocorticoids
serum
|
|
gptkbp:alias
|
gptkb:SGK
gptkb:SGK1
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:diabetes_mellitus
hypertension
|
|
gptkbp:discoveredBy
|
gptkb:Kobayashi_et_al.
|
|
gptkbp:discoveredIn
|
1999
|
|
gptkbp:enzymeCommissionNumber
|
2.7.11.1
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:skeletal_muscle
gptkb:kidney
brain
heart
liver
|
|
gptkbp:fullName
|
Serum/glucocorticoid-regulated kinase 1
|
|
gptkbp:function
|
serine/threonine protein kinase
|
|
gptkbp:gene
|
gptkb:SGK1
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SGK-1
|
|
gptkbp:involvedIn
|
cell survival
response to cellular stress
ion transport regulation
|
|
gptkbp:locatedOnChromosome
|
gptkb:6q23
|
|
gptkbp:molecularWeight
|
49 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Caenorhabditis_elegans
gptkb:Rattus_norvegicus
|
|
gptkbp:phosphorylates
|
gptkb:GSK3β
gptkb:NDRG1
gptkb:FOXO3a
|
|
gptkbp:regulates
|
gptkb:potassium_channels
gptkb:glucose_transporters
epithelial sodium channel (ENaC)
|
|
gptkbp:structure
|
contains kinase domain
|
|
gptkbp:UniProtID
|
gptkb:O00141
|
|
gptkbp:bfsParent
|
gptkb:C._elegans_DAF-16
|
|
gptkbp:bfsLayer
|
7
|