ROCK (Rho-associated kinase)
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:activatedBy |
gptkb:RhoA_GTPase
|
| gptkbp:discoveredIn |
1996
|
| gptkbp:EC_number |
2.7.11.1
|
| gptkbp:encodedBy |
gptkb:ROCK1_gene
gptkb:ROCK2_gene |
| gptkbp:function |
cell proliferation
cell migration regulation of actin cytoskeleton smooth muscle contraction |
| gptkbp:hasIsoform |
gptkb:ROCK1
gptkb:ROCK2 |
| https://www.w3.org/2000/01/rdf-schema#label |
ROCK (Rho-associated kinase)
|
| gptkbp:inhibitedBy |
gptkb:Y-27632
gptkb:fasudil |
| gptkbp:locale |
gptkb:cell_membrane
gptkb:cytoplasm |
| gptkbp:relatedTo |
gptkb:cancer
gptkb:cardiovascular_disease neurological disorders |
| gptkbp:bfsParent |
gptkb:RhoA
|
| gptkbp:bfsLayer |
6
|